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This will make it possible to differentiate soon after the onset of symptoms between different inflammatory joint diseases with different presentations and disease courses. Prognostic criteria RA is not only a heterogeneous disease at presentation but the disease course itself is also highly variable and unpredictable.

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They vary from occupational therapy to surgical synovectomy and from physical therapy and exercise to self-help educational programmes. The mechanism of action of these agents is largely unclear.

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